Testing that we do

There is different types of testing to do on your Golden Retrievers here is the tests and definitions

 ICHTHYOSIS DESCRIPTION:
​Ichthyosis is an autosomal recessive genetic mutation that affects the skin of Golden Retrievers. The mutation prevents the outer layer of the epidermis from forming properly, resulting in skin that becomes darkened and thick and flakes excessively.
The name "Ichthyosis" is derived from the Greek word for fish, which describes the skin's resemblance to fish scales. The most common symptom of ICH-A is excessive flaking of the skin. Other symptoms include areas of hardened skin and hyperpigmentation, which may make the skin appear dirty or blackened. Symptoms can be mild or severe. Evidence of the disease may be detected when the dog is still a puppy, but symptoms may take a year or more to develop. Additionally, symptoms can improve or worsen, depending on stress and hormonal cycles .    

DEGENERATIVE MYELOPATHY
​caused by Mutation of the SOD1 gene is an inherited neurologic disorder of dogs. This mutation is found in many breeds of dog, including the golden retriever. While it is not clear for some of the other breeds, golden retrievers are known to develop degenerative myelopathy associated with this mutation. The variable presentation between breeds suggests that there are environmental or other genetic factors responsible for modifying disease expression. The average age of onset for dogs with degenerative myelopathy is approximately nine years of age. The disease affects the White Matter tissue of the spinal cord and is considered the canine equivalent to amyotrophic lateral sclerosis (Lou Gehrig’s disease) found in humans. Affected dogs usually present in adulthood with gradual muscle Atrophy and loss of coordination typically beginning in the hind limbs due to degeneration of the nerves. The condition is not typically painful for the dog, but will progress until the dog is no longer able to walk. The gait of dogs affected with degenerative myelopathy can be difficult to distinguish from the gait of dogs with hip dysplasia, arthritis of other joints of the hind limbs, or intervertebral disc disease. Late in the progression of disease, dogs may lose fecal and urinary continence and the forelimbs may be affected. Affected dogs may fully lose the ability to walk 6 months to 2 years after the onset of symptoms. Affected medium to large breed dogs, such as the golden retriever, can be difficult to manage and owners often elect euthanasia when their dog can no longer support weight in the hind limbs.      

   Golden Retriever PRA GR-PRA1 & GR-PRA2
Progressive Retinal Atrophy (PRA) is a category of genetic mutations that cause vision loss and blindness. Photoreceptor cells in the retina begin to degenerate, typically progressing from a loss of night vision to complete blindness.
PRA affects many different dog breeds, and these mutations are breed-specific. In Golden Retrievers, two mutations have been identified in addition to prcd-PRA known as GR-PRA1 and GR-PRA2.
Both GR-PRA1 and GR-PRA2 are inherited in an autosomal recessive manner. This means that a dog must inherit a copy of the mutation from each parent to be affected by the disorder. Dogs with one copy of the mutation will not show any signs or symptoms of PRA, however, they can still pass on that mutation to any offspring.
​The AIS PennHIP method has strong scientific foundation as the most effective hip screening tool available for dogs.
AIS PennHIP testing is accurate in puppies as young as 16 weeks of age. It gives an estimate of the risk for painful osteoarthritis (OA) of canine hip dysplasia (CHD) later in life. With this information, preventive and palliative strategies can be recommended by the PennHIP-trained veterinarian.
All dogs can benefit from PennHIP testing. For pet dogs found to be at risk, early intervention can help prevent or lessen the severity of CHD. For working/service dogs, identifying a dog with healthy hips can extend the working life of the dog. For breeding dogs, early detection of at-risk hips can allow the breeder to make early, informed decisions as to which dogs to keep in breeding programs. Neuronal Ceroid Lipofuscinosis
Neuronal Ceroid Lipofuscinosis is a progressive degenerative disease of the central nervous system. In Golden Retrievers, NCL is caused by a two base pair deletion in the CLN5 gene. This causes a frameshift in the genetic coding, leading to a premature termination codon.